| Primary Identifier | MGI:3046463 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 329731 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable receptor ligand activity. Acts upstream of or within negative regulation of microglial cell activation and positive regulation of microglial cell activation. Located in extracellular space. Used to study autism spectrum disorder. Orthologous to human TAFA3 (TAFA chemokine like family member 3). PHENOTYPE: Mice homozygous for a knock-out allele show impaired responses to social novelty, defects in social communication, and increased repetitive behavior. Although only male homozygotes show increased anxiety and repetitive marble-burying behavior, both sexes show increased levels of self-grooming. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
