|  Help  |  About  |  Contact Us

Protein Coding Gene : Cops8 COP9 signalosome subunit 8

Primary Identifier  MGI:1915363 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  108679
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to be involved in negative regulation of cell population proliferation and protein deneddylation. Located in nucleus. Part of COP9 signalosome. Is expressed in several structures, including early embryo; liver; and oocyte. Orthologous to human COPS8 (COP9 signalosome subunit 8).
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality, reduced embryonic size and growth, and reduced to absent outgrowth of the inner cell mass of E3.5 embryos. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 9430009J09 gene,
  • Csn8,
  • 9430009J09Rik,
  • Sgn8,
  • COP9 signalosome subunit 8,
  • AA408242,
  • Cops8,
  • MGI:2138079,
  • expressed sequence AA408242

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

13 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For