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Publication : Chromosomal assignment of the Bcl2-related genes, Bcl2l and Bax, in the mouse and rat.

First Author  Matsuda Y Year  1996
Journal  Cytogenet Cell Genet Volume  74
Issue  1-2 Pages  107-10
PubMed ID  8893813 Mgi Jnum  J:36083
Mgi Id  MGI:83534 Doi  10.1159/000134393
Citation  Matsuda Y, et al. (1996) Chromosomal assignment of the Bcl2-related genes, Bcl2l and Bax, in the mouse and rat. Cytogenet Cell Genet 74(1-2):107-10
abstractText  The Bcl2-related genes, Bax and Bcl2l (formerly called Bclx), are involved in the regulation of apoptotic cell death, and the chromosome location of these two genes was determined in the mouse and rat by fluorescence in situ hybridization. Bcl2l was localized to mouse chromosome 2H1 and rat chromosome 3q41.2, and Bar was localized to mouse chromosome 7B5 and rat chromosome 1q31.2. Both genes mapped in a region of conserved linkage homology between the two species. Molecular linkage analysis using interspecific backcross mice revealed the murine Bcl2l locus at 0.7 cM terminal to D2Mit22, and the murine Bax locus at 0.8 cM terminal to D7Nds5.
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