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Comment :

Type  MGI:General Description  at 48 hr after adenoviral-cre infection, cultured ventricular cardiomyocytes isolated from E14.5 embryos show a significant reduction in BrdU incorporation (19% of controls), suggesting decreased DNA synthesis at 48 hr after adenoviral-cre infection, cultured ventricular cardiomyocytes isolated from E14.5 embryos show a significant reduction in phosphohistone H3 expression (23% of controls), suggesting decreased mitotic activity an MTT-based toxicology assay revealed that cultured adenovirus-cre-infected cardiomyocytes show maximum proliferation on day 2 and significantly decreased proliferation thereafter