Primary Identifier | MGI:98327 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 20605 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables somatostatin receptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway; cellular response to leukemia inhibitory factor; and glutamate receptor signaling pathway. Located in plasma membrane. Is expressed in several structures, including brain; eye; genitourinary system; gut; and respiratory system. Orthologous to human SSTR1 (somatostatin receptor 1). PHENOTYPE: Homozygous null mice display abnormal eye electrophysiology. Mice homozygous for a second targeted mutation display hypoactivity. [provided by MGI curators] |