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Protein Coding Gene : Grk4 G protein-coupled receptor kinase 4
Primary Identifier  MGI:95801 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  14772
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable rhodopsin kinase activity. Predicted to be involved in G protein-coupled receptor internalization. Predicted to be located in several cellular components, including cytosol; dendrite; and neuronal cell body. Predicted to be active in cytoplasm. Is expressed in brain and testis. Human ortholog(s) of this gene implicated in essential hypertension. Orthologous to human GRK4 (G protein-coupled receptor kinase 4).
PHENOTYPE: Mice heterozygous for a knock-out allele are viable, fertile and overtly normal. [provided by MGI curators]
  • synonyms:
  • A830025H08Rik,
  • G protein coupled receptor kinase 2, groucho gene related (Drosophila),
  • G protein-coupled receptor kinase 2, groucho gene related (Drosophila),
  • MGI:1924341,
  • G protein-coupled receptor kinase 4,
  • Grk4,
  • Gprk2l,
  • RIKEN cDNA A830025H08 gene,
  • MGD-MRK-10235
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

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9 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

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Homology

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Interactions

4 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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