Primary Identifier | MGI:3763353 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Myh6-MT2A)15Pne |
Strain of Origin | FVB | Is Recombinase | false |
Is Wild Type | false |
description | 4 lines containing this transgene were created (12, 15, 07 and 01) with over-expression 10- or 130-fold higher than baseline. Identical phenotypes were observed in mice over-expressing 10-fold (line 15) or 130-fold (line 01) higher than baseline. Line 15 was chosen as the representative line. |
molecularNote | This transgene contains human MT2A under the control of the Myh6 promoter along with the first 2 introns and the first three non-coding exons. Expression is cardiac-specific. |