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Comment :

Type  MGI:General Description  LPS-treated mice exhibit an increase in serum IL6 (3.5-fold at 3 hours, 2-fold at 6 hours), IL6 secretion into the peritoneal cavity (3-fold at 3 hours, 32-fold at 6 hours), neutrophil infiltration into the peritoneal cavity, and increased mortality compared with similarly treated wild-type mice