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Publication : Pitpnm1 is expressed in hair cells during development but is not required for hearing.

First Author  Carlisle FA Year  2013
Journal  Neuroscience Volume  248
Pages  620-5 PubMed ID  23820044
Mgi Jnum  J:207051 Mgi Id  MGI:5554342
Doi  10.1016/j.neuroscience.2013.06.045 Citation  Carlisle FA, et al. (2013) Pitpnm1 is expressed in hair cells during development but is not required for hearing. Neuroscience 248C:620-625
abstractText  Deafness is a genetically complex disorder with many contributing genes still unknown. Here we describe the expression of Pitpnm1 in the inner ear. It is expressed in the inner hair cells of the organ of Corti from late embryonic stages until adulthood, and transiently in the outer hair cells during early postnatal stages. Despite this specific expression, Pitpnm1 null mice showed no hearing defects, possibly due to redundancy with the paralogous genes Pitpnm2 and Pitpnm3.
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