| First Author | Tamate HB | Year | 1984 |
| Journal | Science | Volume | 224 |
| Issue | 4654 | Pages | 1241-2 |
| PubMed ID | 6328651 | Mgi Jnum | J:7466 |
| Mgi Id | MGI:55936 | Doi | 10.1126/science.6328651 |
| Citation | Tamate HB, et al. (1984) Action of the e locus of mice in the response of phaeomelanic hair follicles to alpha-melanocyte-stimulating hormone in vitro. Science 224(4654):1241-2 |
| abstractText | Dibutyryl adenosine 3',5'-monophosphate (dibutyryl cyclic AMP) induced eumelanin synthesis in hair bulb melanocytes of recessive yellow (e/e) mice in vitro, whereas alpha-melanocyte-stimulating hormone (alpha-MSH) did not. In contrast, the melanocytes of lethal yellow (Ay/a) mice produced eumelanin in response to both dibutyryl cyclic AMP and alpha-MSH. These results suggest that the e locus controls a mechanism that determines the function of an alpha-MSH receptor. |
