| Primary Identifier | MGI:5438060 | Allele Type | Chemically induced (ENU) |
| Gene | b2b1625Clo | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | B2B/CvDC |
| description | This ENU-induced mutation line was isolated in a screen at the University of Pittsburgh. More than one mutation in this line results in a discernible phenotype in a homozygous recessive screen. At least two segregating phenotype groups are identified. See b2b1625.1Clo and b2b1625.2Clo Summative Diagnosis: Mutant Type 1: Cardiac phenotype: Double outlet right ventricle (DORV)/overriding aorta (Ao), atrioventricular septal defect (AVSD) Noncardiac phenotype: Anopthalmia, duplex kidneys Mutant Type 2: Cardiac phenotype: Persistent truncus arteriosus (PTA), aortic arch anomalies, vascular ring Noncardiac phenotype: Agnathia, microstomia, holoprosencephaly, omphalocele, low set ears |
