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Allele : Tg(Alb-FKBP12/CASP8)#Lsu transgene insertion, Lishan Su

Primary Identifier  MGI:5306232 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Alb-FKBP12/CASP8)#Lsu
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene is comprised of the murine albumin reporter driving expression of a fusion protein of the human FK506 binding protein 1A and human caspase 8 from Ser217-Asp479. Ligand induced dimerization results in activation of caspase 8 and ablation of hepatocytes expressing this transgene.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

2 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele