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Protein Coding Gene : Fgf9 fibroblast growth factor 9

Primary Identifier  MGI:104723 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  14180
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Involved in eye development. Acts upstream of or within several processes, including positive regulation of cell population proliferation; regulation of signal transduction; and skeletal system development. Predicted to be located in basement membrane. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Used to study lung cancer; multiple synostoses syndrome; and pleuropulmonary blastoma. Human ortholog(s) of this gene implicated in kidney cancer and multiple synostoses syndrome 3. Orthologous to human FGF9 (fibroblast growth factor 9).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit reduced size, pulmonary hypoplasia, cardiac dilation, impaired testes development resulting in male-to-female sex reversal, abnormal retina, and neonatal lethality. [provided by MGI curators]
  • synonyms:
  • MGI:2182125,
  • elbow knee synostosis,
  • Eks,
  • fibroblast growth factor 9,
  • Fgf9,
  • MGD-MRK-27086,
  • glia activating factor

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

53 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For