First Author | Vilotte JL | Year | 1992 |
Journal | Gene | Volume | 119 |
Issue | 2 | Pages | 287-92 |
PubMed ID | 1398111 | Mgi Jnum | J:2933 |
Mgi Id | MGI:51449 | Doi | 10.1016/0378-1119(92)90285-w |
Citation | Vilotte JL, et al. (1992) Isolation and characterization of the mouse alpha-lactalbumin-encoding gene: interspecies comparison, tissue- and stage-specific expression. Gene 119(2):287-92 |
abstractText | The murine alpha-lactalbumin-encoding gene (m alpha La) was isolated and completely sequenced. The 2.3-kb transcription unit shared a similar organization with that of its counterparts from other species. Sequence comparison for the proximal 5'-flanking region indicated the presence of a consensus motif that occurs in all milk-protein-encoding genes, except the kappa-casein-encoding gene. This may correspond to the binding site for the recently identified mammary-gland-specific factor. The m alpha La gene occurs in a single copy per haploid genome and is specifically expressed in the mammary gland where it is induced during late pregnancy. |