Primary Identifier | IPR045065 | Type | Family |
Short Name | XPO1/5 |
description | This entry includes exportin-1/5 from eukaryotes.Exportin-1, also known as CRM1, is a nuclear export receptor that have been shown to be involved in U3 snoRNA transport from Cajal bodies to nucleoli []. It also controls the composition of many nucleoplasmic complexes [].Exportin-5 mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos) []. Exportin-5 yeast homologue, also known as Msn5, is involved in nuclear import of replication protein A and export of Far1 and transcription factors Swi5, Swi6, Msn2, and Pho4 [, , ]. Its Arabidopsis homologue, HASTY 1, is involved in the nuclear export of microRNAs (miRNAs) []. |