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Publication : A model for primary melanoma of the CNS implicates NRAS.

First Author  Ciarlo CA Year  2013
Journal  Cancer Discov Volume  3
Issue  4 Pages  382-3
PubMed ID  23580282 Mgi Jnum  J:198340
Mgi Id  MGI:5496446 Doi  10.1158/2159-8290.CD-13-0076
Citation  Ciarlo CA, et al. (2013) A model for primary melanoma of the CNS implicates NRAS. Cancer Discov 3(4):382-3
abstractText  In this issue of Cancer Discovery, Pedersen and colleagues present the first mouse model of primary CNS melanoma, which arises when oncogenic NRAS is expressed from the endogenous Nras promoter in melanocytes during embryogenesis. In support of this model, two pediatric cases of NRAS-mutant primary melanoma of the CNS are identified.
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