|  Help  |  About  |  Contact Us

Protein Domain : Vacuolar protein sorting-associated protein 54, N-terminal

Primary Identifier  IPR019515 Type  Domain
Short Name  VPS54_N
description  This entry represents a domain found in vacuolar protein sorting-associated protein 54 (VPS54), which acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). VPS54 is required to tether the complex to the TGN. However, it is not involved in endocytic recycling [].Proteins containing this domain also includes VPS50 (also known as Syndetin), which is a component of the EARP complex that is involved in endocytic recycling. It is required to tether the EARP complex to recycling endosomes. Nevertheless, it is involved in retrograde transport from early and late endosomes to the TGN [].

0 Child Features

0 Parent Features

5 Protein Domain Regions