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Protein Coding Gene : Fat2 FAT atypical cadherin 2

Primary Identifier  MGI:2685369 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  245827
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable calcium ion binding activity. Predicted to be involved in cell-substrate adhesion; epithelial cell migration; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in Golgi apparatus; anchoring junction; and plasma membrane. Predicted to be active in adherens junction. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; nose; and urinary system. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 45. Orthologous to human FAT2 (FAT atypical cadherin 2).
PHENOTYPE: Mice homozygous for a knock-out allele are healthy, fertile and overtly normal, with no apparent defects in the development of red blood cells or platelets. [provided by MGI curators]
  • synonyms:
  • FAT atypical cadherin 2,
  • gene model 523, (NCBI),
  • Gm523,
  • mKIAA0811,
  • Fath2,
  • EMI2,
  • Fat2,
  • fat tumor suppressor homolog 2 (Drosophila),
  • LOC245827

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For