|  Help  |  About  |  Contact Us

Allele : Sox18<tm1Koop> SRY (sex determining region Y)-box 18; targeted mutation 1, Peter Koopman

Primary Identifier  MGI:2178809 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Sox18
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by replacing sequences encoding the HMG box with a LoxP-neo-LacZ cassette via homologous recombination. RT-PCR analysis of mutant embryos confirmed transcripts of the HMG coding region were absent although transcripts of the trans-activating domain downstream of the LoxP-neo-LacZ cassette were present.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Sox18-,
  • Sox18-
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

14 Publication categories

Trail: Allele