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Protein Coding Gene : Tmed10 transmembrane p24 trafficking protein 10

Primary Identifier  MGI:1915831 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  68581
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable cargo receptor activity; protein transmembrane transporter activity; and syntaxin binding activity. Involved in several processes, including positive regulation of interleukin-1 production; positive regulation of protein secretion; and vesicle targeting, to, from or within Golgi. Located in zymogen granule membrane. Part of gamma-secretase complex. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human TMED10 (transmembrane p24 trafficking protein 10).
PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality before implantation. Heterozygous mice display abnormalities of the Golgi apparatus. [provided by MGI curators]
  • synonyms:
  • Tmed10,
  • transmembrane p24 trafficking protein 10,
  • RIKEN cDNA 1110014C03 gene,
  • 1110014C03Rik,
  • p23,
  • p24delta1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

13 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For