First Author | Kosuga K | Year | 1995 |
Journal | Biochim Biophys Acta | Volume | 1260 |
Issue | 3 | Pages | 345-8 |
PubMed ID | 7873613 | Mgi Jnum | J:23128 |
Mgi Id | MGI:70915 | Doi | 10.1016/0167-4781(94)00245-x |
Citation | Kosuga K, et al. (1995) Nucleotide sequence of a cDNA for mouse squalene epoxidase. Biochim Biophys Acta 1260(3):345-8 |
abstractText | A full-length cDNA encoding mouse squalene epoxidase was isolated by screening a mouse liver cDNA library with the rat squalene epoxidase gene as a probe. The cDNA had an open reading frame for a 572 amino acid polypeptide with a calculated molecular mass of 63.8 kDa. The predicted amino acid sequence of the mouse enzyme contained an FAD-binding motif, and was 93% identical to that of the rat enzyme. The former is one amino acid shorter than the latter. Blotting analyses showed that the mRNA is 2.8 kb in size and that a single copy of the gene is present in the mouse genome. |