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Allele : Pik3ca<tm1.1Waph> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1.1, Wayne A Phillips
Primary Identifier  MGI:5427579 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Pik3ca
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 20 was floxed. An addtional modified exon 20 was inserted downstream of the endogenous exon. The modified exon 20 contains nucleotide substitutions (CAT to AGG) that result in the amino acid substitution of arginine for histidine at position 1047 (H1047R). Flp-mediated recombination removed the FRT-flanked neo cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Pik3ca<Lat-H1047R>,
  • Pik3ca<Lat-H1047R>,
  • p110a<HR>,
  • Pik3ca<H1047R>,
  • Pik3ca<H1047R>,
  • p110a<HR>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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28 Publication categories

Trail: Allele




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