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Allele : Hprt1<tm4(KRT14-ROCK2*/ERT)Bicrq> hypoxanthine phosphoribosyltransferase 1; targeted mutation 4, Cancer Research UK Beatson Institute
Primary Identifier  MGI:6771468 Allele Type  Targeted
Attribute String  Inducible, Inserted expressed sequence, Reporter Gene  Hprt1
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Induced With  tamoxifen Is Recombinase  false
Is Wild Type  false
molecularNote  The targeting construct inserted upstream of exon 2 a Keratin 14 (KRT14) promoter, EGFP reporter gene, human ROCK2 (kinase-dead version) fused to an engineered version of the hormone binding domain of the estrogen receptor (ERT), and the wild-type promoter and exon one of the endogenous gene.
  • mutations:
  • Insertion
  • synonyms:
  • K14-KD2:ER,
  • Hprt<tm1(K14-ROCK2/ER)Bicrq>,
  • K14-KD2:ER,
  • Hprt<tm1(K14-ROCK2/ER)Bicrq>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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