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Protein Coding Gene : Lrrc8b leucine rich repeat containing 8 family, member B

Primary Identifier  MGI:2141353 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  433926
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to contribute to volume-sensitive anion channel activity. Predicted to be involved in aspartate transmembrane transport; cyclic-GMP-AMP transmembrane import across plasma membrane; and monoatomic anion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human LRRC8B (leucine rich repeat containing 8 VRAC subunit B).
PHENOTYPE: Mice homozygous for a null allele exhibit normal response to viral infection. [provided by MGI curators]
  • synonyms:
  • Lrrc8b,
  • leucine rich repeat containing 8 family, member B,
  • MGI:1917430,
  • 2210408K08Rik,
  • expressed sequence R75581,
  • RIKEN cDNA 2210408K08 gene,
  • R75581

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For