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Protein Coding Gene : St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

Primary Identifier  MGI:106020 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  20450
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. Involved in sialylation. Located in early endosome and recycling endosome. Is expressed in several structures, including central nervous system; future brain; genitourinary system; gut; and retina. Orthologous to human ST8SIA2 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2).
PHENOTYPE: Homozygous null mice display abnormal mossy fiber morphology, increased exploration in new environment and impaired fear responses. [provided by MGI curators]
  • synonyms:
  • sialyltransferase 8 (alpha-2, 8-sialyltransferase) B,
  • ST8SiaII,
  • Siat8b,
  • MGD-MRK-33702,
  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2,
  • MGI:2141905,
  • AI323367,
  • expressed sequence AI323367,
  • St8sia2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

14 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For