| First Author | Graves PE | Year | 1995 |
| Journal | Biochem Biophys Res Commun | Volume | 208 |
| Issue | 2 | Pages | 624-8 |
| PubMed ID | 7695616 | Mgi Jnum | J:23975 |
| Mgi Id | MGI:71769 | Doi | 10.1006/bbrc.1995.1384 |
| Citation | Graves PE, et al. (1995) Sequence variation in the 5', putative promoter of Sry and its possible relevance to the C57BL/6J-YDOM sex reversal. Biochem Biophys Res Commun 208(2):624-8 |
| abstractText | Sry is the testes determining factor gene located on the Y chromosome. We sought sequence variation in potential promoter regions that might explain the gradiation in sex reversal seen when different domesticus strains are bred to C57BL/6J females since sequence variation previously found in the coding region is not sufficient to explain it. Dideoxy sequencing identified a 10 bp deletion in the 5' flanking region limited to YDOM chromosomes of weak effect. A PCR strategy to search for deletions in this region disclosed another deletion which was shown to be different by sequencing. |
