| Primary Identifier | IPR046880 | Type | Repeat |
| Short Name | TPR-S |
| description | This entry represents a sensor domain consisting of 7 TPR repeats forming a tightly-wound solenoid structure harbouring a deep central pocket. The TPR-S binding pocket is lined with several conserved aromatic and polar residues predicted to bind a NAD -derived nucleotide in prokaryotic NAD -derived nucleotide-activated effector conflict systems. It has been acquired at the base of the choanoflagellate-animal lineage as a core component of the ASK signalosome []. |
