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Protein Coding Gene : Anapc1 anaphase promoting complex subunit 1
Primary Identifier  MGI:103097 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  17222
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable molecular adaptor activity. Predicted to be involved in anaphase-promoting complex-dependent catabolic process; metaphase/anaphase transition of mitotic cell cycle; and protein K11-linked ubiquitination. Predicted to act upstream of or within cell division. Located in nucleus. Is expressed in brain; cerebellum; and cerebral cortex. Human ortholog(s) of this gene implicated in Rothmund-Thomson syndrome. Orthologous to human ANAPC1 (anaphase promoting complex subunit 1).
  • synonyms:
  • expressed sequence AI047775,
  • MGI:1923795,
  • tsg24,
  • Mcpr,
  • Anapc1,
  • expressed sequence AI853536,
  • MGI:2138834,
  • MGI:2139095,
  • 2610021O03Rik,
  • AI853536,
  • RIKEN cDNA 2610021O03 gene,
  • meiotic check point regulator,
  • AW547281,
  • AI047775,
  • Apc1,
  • anaphase promoting complex subunit 1,
  • MGI:2139376,
  • MGD-MRK-23961,
  • expressed sequence AW547281
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Features --> Cross References

Genome

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2 Involved In Mutations

Trail: ProteinCodingGene

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

39 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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