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Protein Coding Gene : Vps26b VPS26 retromer complex component B

Primary Identifier  MGI:1917656 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  69091
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane and retrograde transport, endosome to Golgi. Acts upstream of or within cellular response to type II interferon. Located in early endosome; late endosome; and phagocytic vesicle. Part of retromer complex. Is active in glutamatergic synapse; postsynaptic early endosome; and postsynaptic recycling endosome. Is expressed in several structures, including central nervous system; dorsal root ganglion; male reproductive system; sensory organ; and urinary system. Orthologous to human VPS26B (VPS26 retromer complex component B).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal behavior, growth, and health. [provided by MGI curators]
  • synonyms:
  • VPS26 retromer complex component B,
  • RIKEN cDNA 1810012I05 gene,
  • Vps26b,
  • AI848392,
  • MGI:2143146,
  • RIKEN cDNA 2310075A12 gene,
  • MGI:1916341,
  • 2310075A12Rik,
  • 1810012I05Rik,
  • expressed sequence AI848392

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