First Author | Sakakibara Y | Year | 1998 |
Journal | Biochem Biophys Res Commun | Volume | 247 |
Issue | 3 | Pages | 681-6 |
PubMed ID | 9647753 | Mgi Jnum | J:48327 |
Mgi Id | MGI:1267177 | Doi | 10.1006/bbrc.1998.8872 |
Citation | Sakakibara Y, et al. (1998) Molecular cloning, expression, and functional characterization of novel mouse sulfotransferases. Biochem Biophys Res Commun 247(3):681-6 |
abstractText | Nucleotide sequences of two mouse cDNAs encoding new sulfotransferase enzymes were determined. Analysis of the deduced amino acid sequences revealed that one represents a novel member of the phenol sulfotransferase family and the other is highly homologous to human SULT2B1 hydroxysteroid sulfotransferases. The recombinant enzymes, transiently expressed in COS-7 cells, were characterized with respect to their substrate specificity using a variety of substrates for different types of sulfotransferases. The tissue-specific expression of these two new mouse sulfotransferases was examined by Northern blot analysis. |