First Author | Rebocho AP | Year | 2011 |
Journal | Cancer Discov | Volume | 1 |
Issue | 2 | Pages | 98-9 |
PubMed ID | 22318779 | Mgi Jnum | J:189130 |
Mgi Id | MGI:5444375 | Doi | 10.1158/2159-8290.CD-11-0118 |
Citation | Rebocho AP, et al. (2011) New insight puts CRAF in sight as a therapeutic target. Cancer Discov 1(2):98-9 |
abstractText | By selectively depleting components of the RAF-MEK-ERK pathway in transgenic mice, it is now shown in 2 studies that CRAF is critical for signaling to MEK downstream of oncogenic Kras and that BRAF is not required. |