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Allele : Cd3d<tm1Kap> CD3 antigen, delta polypeptide; targeted mutation 1, Dietmar J Kappes

Primary Identifier  MGI:2180760 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd3d
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2, which encodes most of the protein, was replaced with a neomycin selection cassette. RT-PCR and Northern blot analyses of homozygous mutant mice indicated an absence of normal transcript. Aberrant transcripts were reported. Normal levels of Cd3e and Cd3g transcript were detected.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CD3delta-deficient,
  • delta<->,
  • CD3delta-deficient,
  • delta<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

13 Publication categories

Trail: Allele