Primary Identifier | MGI:2180760 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd3d |
Transmission | Germline | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2, which encodes most of the protein, was replaced with a neomycin selection cassette. RT-PCR and Northern blot analyses of homozygous mutant mice indicated an absence of normal transcript. Aberrant transcripts were reported. Normal levels of Cd3e and Cd3g transcript were detected. |