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Protein Coding Gene : Dscam DS cell adhesion molecule

Primary Identifier  MGI:1196281 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  13508
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables netrin receptor binding activity and protein tyrosine kinase binding activity. Involved in several processes, including netrin-activated signaling pathway; neuron development; and positive regulation of axon extension involved in axon guidance. Acts upstream of or within dendrite morphogenesis; locomotory behavior; and post-embryonic retina morphogenesis in camera-type eye. Located in several cellular components, including dendrite; growth cone; and neuronal cell body. Is expressed in several structures, including central nervous system; peripheral nervous system; sensory organ; skin; and testis. Orthologous to human DSCAM (DS cell adhesion molecule).
PHENOTYPE: Mice homozygous for a null allele exhibit background-sensitive perinatal lethality associated with respiratory distress, altered C4 ventral root and pre-inspiratory neuron signaling, and abnormal response to hypercapnia. [provided by MGI curators]
  • synonyms:
  • DS cell adhesion molecule,
  • 4932410A21Rik,
  • RIKEN cDNA 4932410A21 gene,
  • Down syndrome cell adhesion molecule,
  • MGI:1926011,
  • Dscam

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

7 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For