| Type | MGI:General | Description | at 3 months of age, serum enzymatic activities of the lysosomal hydrolases beta-hexosaminidase, beta-galactosidase, alpha-mannosidase, and beta-mannosidase are increased by 2.5- to 30-fold relative to wild-type controls at 4 months of age, enzymatic activities of beta-hexosaminidase, alpha-mannosidase, and beta-glucoronidase are increased by 1.5-fold, whereas beta-galactosidase is decreased by 30%, as measured in whole brain lysates |
