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Protein Coding Gene : Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3

Primary Identifier  MGI:96660 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  16491
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable delayed rectifier potassium channel activity and outward rectifier potassium channel activity. Predicted to be involved in action potential and potassium ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport. Located in axon. Is expressed in brain; heart; olfactory cortex mantle layer; and telencephalon. Orthologous to human KCNA3 (potassium voltage-gated channel subfamily A member 3).
PHENOTYPE: Mice homozygous for a knock-out allele display no apparent immune system defects. Mice homozygous for a different knock-out allele show reduced body weight, increased basal metabolic rate, resistance to diet-induced obesity, increased insulin sensitivity, and altered peripheral glucose metabolism. [provided by MGI curators]
  • synonyms:
  • mouse K+ channel gene 3 (cortical),
  • Kca1-3,
  • K<+> channel, A current, subtype 1, gene 3,
  • Mk-3,
  • MGD-MRK-12250,
  • MGD-MRK-11556,
  • Kcna3,
  • Kv1.3,
  • potassium voltage-gated channel, shaker-related subfamily, member 3,
  • MGD-MRK-11564

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For