| Primary Identifier | MGI:1929289 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 56436 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including endopeptidase activator activity; protease binding activity; and proteasome binding activity. Involved in several processes, including germ cell development; gonad development; and positive regulation of growth hormone receptor signaling pathway. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of proteasome regulatory particle, lid subcomplex. Is expressed in several structures, including genitourinary system; liver; sensory organ; and skeleton. Orthologous to human ADRM1 (ADRM1 26S proteasome ubiquitin receptor). PHENOTYPE: Mice homozygous for a gene trap allele exhibit decreased birth weight, reduced competition for food, postnatal lethality, infertility, impaired sperm and oocyte development, increased peripheral CD4+ and CD8+ T cells, and increased serum GH and FSH levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
