| Primary Identifier | IPR000593 | Type | Domain |
| Short Name | RasGAP_C |
| description | This domain can be found in the C terminus of the IQGAP family members, including human IQGAP1/2/3, S. cerevisiae Iqg1 and S. pombe Rng2. Some members function in cytoskeletal remodelling []. Human IQGAP1 is a scaffolding protein that can assemble multi-protein complexes involved in cell-cell interaction, cell adherence, and movement via actin/tubulin-based cytoskeletal reorganization []. IQGAP1 is also a regulator of the MAPK and Wnt/beta-catenin signaling pathways []. Iqg1 and Rng2 are required for actomyosin ring construction during cytokinesis [, ]. |
