| Primary Identifier | MGI:2449306 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Psen1 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A single loxP site was inserted into intron 1 and a loxP-flanked hygromycin and thymidine kinase selection cassette was inserted into intron 3. Exons 2 and 3 and the drug selection cassette were removed in ES cells by transient Cre expression in ES cells prior to the production of mice. The final allele has a single loxP site in place of exons 2 and 3. |
