Primary Identifier | MGI:1913103 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 60363 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to act upstream of or within monoatomic ion transport. Located in lateral plasma membrane. Is expressed in intestine epithelium; lung; metanephros; pancreas; and stomach. Orthologous to human CLDN15 (claudin 15). PHENOTYPE: Mice homozygous for a knock-out allele are viable and grow normally with an enlarged upper small intestinal phenotype (megaintestine) resulting from enhanced proliferation of normal cryptic cells after weaning. [provided by MGI curators] |