|  Help  |  About  |  Contact Us

Allele : Tg(ITGA2)1075Fmw transgene insertion 1075, Fiona M Watt
Primary Identifier  MGI:1926489 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(ITGA2)1075Fmw
Inheritance Mode  Not Specified Strain of Origin  (CBA x C57BL/10)F1
Is Recombinase  false Is Wild Type  false
description  See also Tg(ITGA2)1067Fmw and Tg(ITGA2)1070Fmw for variability in transgene copy number using this construct. Severity of described phenotypes correlates to the copy number of the transgenes.
molecularNote  Overexpression of human integrin alpha 2 (ITGA2) in the suprabasal layers of the epidermis driven by the human involucrin (IVL) promoter. 22 copies of this gene were inserted, as determined by southern blotting.
  • mutations:
  • Insertion
  • synonyms:
  • 1075 alpha2,
  • 1075 alpha2
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom