Primary Identifier | MGI:104749 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 18413 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables cytokine activity. Acts upstream of or within several processes, including behavioral response to pain; negative regulation of meiotic nuclear division; and positive regulation of peptidyl-tyrosine phosphorylation. Predicted to be located in extracellular space. Is expressed in aorta-gonad-mesonephros; future spinal cord; genitourinary system; liver; and submandibular gland. Orthologous to human OSM (oncostatin M). PHENOTYPE: Homozygous mutant mice display decreased noxious responses in models of acute thermal, mechanical, chemical, and visceral pain. [provided by MGI curators] |