| First Author | Arroyo S | Year | 2012 |
| Journal | J Neurosci | Volume | 32 |
| Issue | 11 | Pages | 3859-64 |
| PubMed ID | 22423106 | Mgi Jnum | J:253603 |
| Mgi Id | MGI:6099170 | Doi | 10.1523/JNEUROSCI.0115-12.2012 |
| Citation | Arroyo S, et al. (2012) Prolonged disynaptic inhibition in the cortex mediated by slow, non-alpha7 nicotinic excitation of a specific subset of cortical interneurons. J Neurosci 32(11):3859-64 |
| abstractText | Cholinergic activation of nicotinic receptors in the cortex plays a critical role in arousal, attention, and learning. Here we demonstrate that cholinergic axons from the basal forebrain of mice excite a specific subset of cortical interneurons via a remarkably slow, non-alpha7 nicotinic receptor-mediated conductance. In turn, these inhibitory cells generate a delayed and prolonged wave of disynaptic inhibition in neighboring cortical neurons, altering the spatiotemporal pattern of inhibition in cortical circuits. |
