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Protein Domain : Natriuretic peptide, C type

Primary Identifier  IPR002406 Type  Family
Short Name  C_natriurtcpep
description  Atrial natriuretic peptides (ANPs) are vertebrate hormones that play an important role in the control ofcardiovascular homeostatis, and sodium and water balance in general [, ].There are different NPs that vary in length but share a common core. All are processed from a single precursor.A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins. The familyof NPs includes structurally-related peptides that elicit similar pharmacological spectra. Amongst these arebrain natriuretic peptide (BNP); C-type natriuretic peptide (CNP); ventricular natriuretic peptide (VNP)[]; and Dendroaspis angusticeps (Eastern green mamba) natriuretic peptide (DNP) []C-type natriuretic peptide has vasorelaxant and cGMP-stimulating activities.

0 Child Features

1 Parent Features

9 Protein Domain Regions