Primary Identifier | IPR002406 | Type | Family |
Short Name | C_natriurtcpep |
description | Atrial natriuretic peptides (ANPs) are vertebrate hormones that play an important role in the control ofcardiovascular homeostatis, and sodium and water balance in general [, ].There are different NPs that vary in length but share a common core. All are processed from a single precursor.A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins. The familyof NPs includes structurally-related peptides that elicit similar pharmacological spectra. Amongst these arebrain natriuretic peptide (BNP); C-type natriuretic peptide (CNP); ventricular natriuretic peptide (VNP)[]; and Dendroaspis angusticeps (Eastern green mamba) natriuretic peptide (DNP) []C-type natriuretic peptide has vasorelaxant and cGMP-stimulating activities. |