Primary Identifier | MGI:2146851 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 224481 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables rRNA (adenine-N6,N6-)-dimethyltransferase activity. Involved in rRNA methylation. Located in mitochondrion. Is expressed in cerebral cortex ventricular layer; early conceptus; and secondary oocyte. Orthologous to human TFB1M (transcription factor B1, mitochondrial). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality associated with developmental defects and reduced mitochondrial function at E8.5. [provided by MGI curators] |