| Type | MGI:General | Description | ovaries show reduced protein levels of the catalytic and modifier subunits of glutamate-cysteine ligase (GCL), the rate-limiting enzyme in glutathione synthesis, with 36% lower protein levels of GCLC and 45% lower protein levels of GCLM ovarian mRNA levels of Gstm1 (glutathione S-transferase, mu 1) and Ephx1 (epoxide hydrolase 1, microsomal) are 67% and 91% lower than in wild-type controls |
