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Publication : Cloning and characterization of a cDNA for a new mouse T cell growth factor (P40).

First Author  Van Snick J Year  1989
Journal  J Exp Med Volume  169
Issue  1 Pages  363-8
PubMed ID  2521242 Mgi Jnum  J:9515
Mgi Id  MGI:57975 Doi  10.1084/jem.169.1.363
Citation  Van Snick J, et al. (1989) Cloning and characterization of a cDNA for a new mouse T cell growth factor (P40). J Exp Med 169(1):363-8
abstractText  Recently, we described a murine helper T cell-derived molecule with T cell growth factor activity that is functionally and structurally distinct from IL-2, IL-4, and other known growth factors. This molecule, designated P40, was identified as a glycoprotein capable of supporting antigen-independent growth of certain helper T cell clones. Here, we report the cloning and expression of a cDNA for this new growth factor. The predicted mature protein is a cationic cysteine-rich polypeptide of 14 kD without significant homology to previously sequenced proteins.
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