| First Author | Uyttenhove C | Year | 1988 |
| Journal | Proc Natl Acad Sci U S A | Volume | 85 |
| Issue | 18 | Pages | 6934-8 |
| PubMed ID | 3137580 | Mgi Jnum | J:14595 |
| Mgi Id | MGI:62759 | Doi | 10.1073/pnas.85.18.6934 |
| Citation | Uyttenhove C, et al. (1988) Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity. Proc Natl Acad Sci U S A 85(18):6934-8 |
| abstractText | Antigen-independent cell lines were derived from mouse helper T-cell clones by culture in autologous supernatant obtained after stimulation with concanavalin A. A factor, termed P40, supporting the growth of these lines was purified and characterized as a basic 32- to 39-kDa single-chain glycoprotein functionally distinct from previously identified T-cell growth factors and apparently unrelated structurally to any known protein. Of a number of cell lines, only helper T cells responded to P40, and this response was not mediated by either interleukin 2 or interleukin 4. |
