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Protein Domain : DIS3-like exonuclease 2

Primary Identifier  IPR028591 Type  Family
Short Name  DIS3L2
description  DIS3-like exonuclease 2 (DIS3L2) is a 3'-5'-exoribonuclease that specifically recognises RNAs polyuridylated at their 3' end and mediates their degradation. It plays an important role in the mRNA degradation pathway alternative to degradation by Xrn1 and the exosome [, ]. This entry also includes DIS3L2 plant homologue, SUPPRESSOR OF VARICOSE (SOV) (At1g77680), which functions in cytoplasmic mRNA decay and suppresses Arabidopsis decapping mutant phenotypes [].

0 Child Features

0 Parent Features

1 Protein Domain Regions