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Allele : Pitx2<tm4(cre)Jfm> paired-like homeodomain transcription factor 2; targeted mutation 4, James F Martin

Primary Identifier  MGI:2445429 Allele Type  Targeted
Attribute String  Recombinase Gene  Pitx2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  true Is Wild Type  false
molecularNote  Exon 5, which encodes a portion of the homeodomain, was disrupted by the insertion of a cassette containing IRES, cre recombinase, lacZ, and neo. In situ hybridization results showed that the expression pattern of cre was similar to that of the endogenous gene. The neo was removed by crossing to Flp-expressing mice.
  • mutations:
  • Insertion
  • synonyms:
  • Pitx2<creneo>,
  • Pitx2-Cre,
  • delta abc<creneo>,
  • Pitx2-Cre,
  • Pitx2<creneo>,
  • delta abc<creneo>,
  • Pitx2 delta abc<creneo>,
  • Pitx2 delta abc<creneo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

1 Driven By

Trail: Allele

32 Publication categories

Trail: Allele