|  Help  |  About  |  Contact Us

Comment :

Type  MGI:General Description  at 5.5 weeks of age, all proliferative and crescentic lesions observed in mutant glomeruli are exclusively composed of activated (KI67-positive) parietal epithelial cells (PECs), indicating PEC activation and proliferation in response to rapid and severe podocyte loss; a marker for macrophages, CD68, is negative in the cellular crescents